Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12158739 | 1.00 | L3MBTL1 (0.76) | L3MBTL1ALDH1A1FFAR1NPC1RAB9A | |
| SCHEMBL12174632 | 0.94 | L3MBTL1 (0.86) | L3MBTL1ALDH1A1FFAR1NPC1RAB9A | |
| SCHEMBL7717108 | 0.94 | L3MBTL1 (0.86) | L3MBTL1ALDH1A1FFAR1NPC1RAB9A | |
| SCHEMBL16624890 | 0.88 | L3MBTL1 (0.81) | L3MBTL1ALDH1A1FFAR1NPC1RAB9A | |
| SCHEMBL19071295 | 0.88 | L3MBTL1 (0.81) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28114650 | 0.86 | ATM (0.66) | L3MBTL1ALDH1A1NPC1SMN1; SMN2TDP1 | |
| SCHEMBL2581702 | 0.86 | ATM (0.66) | L3MBTL1ALDH1A1NPC1SMN1; SMN2TDP1 | |
| SCHEMBL12158645 | 0.86 | ATM (0.66) | L3MBTL1ALDH1A1NPC1SMN1; SMN2TDP1 | |
| SCHEMBL16624900 | 0.86 | L3MBTL1 (0.76) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16624892 | 0.85 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304581-B2 | Method of enantioselective addition to enones | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-11-06 | — | — | US | disclosed |
| US-20110282101-A1 | METHOD OF ENANTIOSELECTIVE ADDITION TO ENONES | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-11-17 | — | — | US | disclosed |
| US-6380392-B1 | COMPLEXES | THE PENN STATE RESEARCH FOUNDATION | 2002-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282101-A1 | METHOD OF ENANTIOSELECTIVE ADDITION TO ENONES | CPNE4, ENY2, CYP3A4 | L3MBTL1 3225/4885ALDH1A1 1344/4885FFAR1 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.