SCHEMBL25866743

SCHEMBL25866743

O=CN1CCC(NCCOc2ccc3c(ccc4occ(C5CCC(=O)NC5=O)c43)c2)CC1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.40
BCHE P06276 4/20 0.39
ACHE P22303 4/20 0.39
XDH P47989 2/20 0.35
CRBN Q96SW2 1/20 0.33
HPGD P15428 1/20 0.33
ATF4 P18848 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23634830 0.91 MAOB (0.41) MAOBBCHEACHEXDHCRBN
SCHEMBL23634796 0.91 MAOB (0.41) MAOBBCHEACHEXDHCRBN
SCHEMBL23634829 0.91 MAOB (0.41) MAOBBCHEACHEXDHCRBN
SCHEMBL23635035 0.89 XDH (0.43) MAOBBCHEACHEXDHCRBN
SCHEMBL23635036 0.89 XDH (0.43) MAOBBCHEACHEXDHCRBN
SCHEMBL23634954 0.89 XDH (0.43) MAOBBCHEACHEXDHCRBN
SCHEMBL23634943 0.88 XDH (0.37) MAOBBCHEACHEXDHCRBN
SCHEMBL23635037 0.88 XDH (0.37) MAOBBCHEACHEXDHCRBN
SCHEMBL23634948 0.88 XDH (0.37) MAOBBCHEACHEXDHCRBN
SCHEMBL23634987 0.88 XDH (0.37) MAOBBCHEACHEXDHCRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848363-B1 TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND MEDSHINE DISCOVERY INC (CN) 2023-07-19 EP disclosed