SCHEMBL2586684

SCHEMBL2586684

[c]1oc2ccccc2c1-c1cccc2c1ccc1c3ccccc3ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.47
ALDH1A1 P00352 7/20 0.40
HSD17B10 Q99714 6/20 0.40
TDP1 Q9NUW8 3/20 0.40
TSHR P16473 2/20 0.40
CYP2A6 P11509 1/20 0.40
HPGD P15428 5/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
PAX8 Q06710 1/20 0.36
CYP1A2 P05177 4/20 0.36
HIF1A Q16665 3/20 0.36
MAPK1 P28482 3/20 0.36
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6256201 0.91 MAPT (0.44) ALDH1A1HSD17B10TDP1TSHRCYP2A6
SCHEMBL5984762 0.77 IKBKE (0.44) ALDH1A1HSD17B10HPGDMAPTKDM4E
SCHEMBL7972358 0.74 CYP2A6 (0.38) ALDH1A1CYP2A6HPGDCYP1A2HIF1A
SCHEMBL11728712 0.74 AKR1C3 (0.42) ALDH1A1HSD17B10TDP1HPGDMAPT
SCHEMBL29769915 0.73 HPRT1 (0.78) HPRT1ALDH1A1HSD17B10TDP1TSHR
SCHEMBL29445992 0.73 HPRT1 (0.78) HPRT1ALDH1A1HSD17B10TDP1TSHR
SCHEMBL593261 0.73 HPRT1 (0.78) HPRT1ALDH1A1HSD17B10TDP1TSHR
SCHEMBL30021848 0.71 HPRT1 (0.74) HPRT1ALDH1A1HSD17B10TDP1TSHR
SCHEMBL442130 0.71 HPRT1 (0.74) HPRT1ALDH1A1HSD17B10TDP1TSHR
SCHEMBL30103588 0.71 HPRT1 (0.74) HPRT1ALDH1A1HSD17B10TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9269911-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-02-23 US disclosed
EP-2564441-A1 ORGANIC LIGHT-EMITTING DEVICE Canon Kabushiki Kaisha (JP) 2013-03-06 EP disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed
WO-2011136156-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-11-03 WO disclosed