Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797314 | 0.81 | MCHR1 (0.65) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL5447992 | 0.80 | MCHR1 (0.56) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13794773 | 0.79 | MCHR1 (0.65) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL25309780 | 0.78 | APP (0.67) | NPY5RAPPBCHEACHEPDE5A | |
| SCHEMBL13793341 | 0.78 | MCHR1 (0.74) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13796262 | 0.78 | MCHR1 (0.63) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13795984 | 0.78 | MCHR1 (0.63) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL25867149 | 0.77 | APP (0.66) | NPY5RAPPBCHEACHEPDE5A | |
| SCHEMBL5529932 | 0.76 | MCHR1 (0.66) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL5529927 | 0.76 | MCHR1 (0.66) | MCHR1ADRA2ANPY5RHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133221-A2 | SMARCA2/4 INHIBITION AS A STRATEGY TO TREAT TUMORS THAT HARBOR ABERRANT BAF ASSEMBLIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-13 | — | — | WO | disclosed |