Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.66 |
| ▸ | BCHE | P06276 | 6/20 | 0.66 |
| ▸ | ACHE | P22303 | 6/20 | 0.66 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.58 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309780 | 0.99 | APP (0.67) | APPBCHEACHECTNNB1TCF7L2 | |
| SCHEMBL25867456 | 0.91 | APP (0.62) | APPBCHEACHECTNNB1TCF7L2 | |
| SCHEMBL25867340 | 0.90 | APP (0.64) | APPBCHEACHECTNNB1TCF7L2 | |
| SCHEMBL25867224 | 0.86 | BCHE (0.61) | APPBCHEACHECTNNB1TCF7L2 | |
| SCHEMBL25867222 | 0.86 | APP (0.70) | APPBCHEACHECTNNB1TCF7L2 | |
| SCHEMBL2588892 | 0.83 | RAD52 (0.74) | APPBCHEACHEUSP1WDR48 | |
| SCHEMBL25867223 | 0.82 | APP (0.71) | APPBCHEACHECTNNB1TCF7L2 | |
| SCHEMBL25867225 | 0.82 | CCR4 (0.63) | APPBCHEACHEAURKADAPK3 | |
| SCHEMBL25867300 | 0.81 | BCHE (0.71) | APPBCHEACHECTNNB1TCF7L2 | |
| SCHEMBL30896249 | 0.80 | APP (0.60) | APPBCHEACHENPY5RAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133221-A2 | SMARCA2/4 INHIBITION AS A STRATEGY TO TREAT TUMORS THAT HARBOR ABERRANT BAF ASSEMBLIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-13 | — | — | WO | disclosed |