SCHEMBL258674

SCHEMBL258674

Cc1cccc(CC(C)C)c1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 5/20 0.76
GABRB2 P47870 5/20 0.76
ALDH1A1 P00352 2/20 0.52
TRPA1 O75762 2/20 0.46
ELANE P08246 2/20 0.44
CTSG P08311 1/20 0.44
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA12 O43570 2/20 0.40
CA9 Q16790 2/20 0.40
HPGD P15428 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HSD17B10 Q99714 2/20 0.39
SOS2 Q07890 1/20 0.38
FAAH O00519 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
GABRB1 P18505 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL864085 0.87 GABRA1 (1.00) GABRA1GABRB2ALDH1A1ELANECTSG
SCHEMBL9247390 0.86 GABRA1 (0.55) GABRA1GABRB2ALDH1A1TRPA1CA1
SCHEMBL14478220 0.84 SOS2 (0.54) GABRA1GABRB2ALDH1A1TRPA1SOS2
SCHEMBL8997130 0.82 GABRA1 (0.52) GABRA1GABRB2ALDH1A1TRPA1CA1
SCHEMBL4443328 0.82 GABRA1 (0.52) GABRA1GABRB2ALDH1A1TRPA1CA1
SCHEMBL1053654 0.81 GABRA1 (0.79) GABRA1GABRB2ALDH1A1TRPA1ELANE
SCHEMBL14995226 0.81 GABRA1 (0.79) GABRA1GABRB2ELANECTSGCA1
SCHEMBL9349490 0.80 GABRA1 (0.48) GABRA1GABRB2ALDH1A1TRPA1CA1
SCHEMBL24918341 0.80 GABRA1 (0.48) GABRA1GABRB2ALDH1A1TRPA1ELANE
SCHEMBL9658390 0.80 GABRA1 (0.48) GABRA1GABRB2ALDH1A1TRPA1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7384434-B2 Reaction of phenols with intermediate triazines AFTON CHEMICAL CORPORATION (US) 2008-06-10 US claimed
US-20060196111-A1 Fuel additive composition AFTON CHEMICAL CORPORATION 2006-09-07 US claimed
US-20060196107-A1 Cyclic mannich products AFTON CHEMICAL CORPORATION 2006-09-07 US claimed
EP-1645614-A1 Preparation of amine derivates from nitriles and phenols Afton Chemical Corporation (US) 2006-04-12 EP claimed
US-20060059771-A1 Preparation of amine derivates from nitriles and phenols AFTON CHEMICAL CORPORATION 2006-03-23 US claimed
US-20050268538-A1 Reaction of phenols with intermediate triazines AFTON CHEMICAL CORPORATION 2005-12-08 US claimed
WO-1996037535-A1 METHOD OF PREPARING POLY(PHENYLENE OXIDES) IN CARBON DIOXIDE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1996-11-28 WO claimed
US-20240132791-A1 FUEL COMPOSITION AFTON CHEMICAL CORPORATION 2024-04-25 US disclosed
WO-2024068384-A1 FUEL COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2024-04-04 WO disclosed
EP-4345152-A1 FUEL COMPOSITION Afton Chemical Corporation (US) 2024-04-03 EP disclosed
CN-117801850-A Fuel composition 雅富顿化学公司 2024-04-02 CN disclosed
CN-109929103-B Method for preparing high-intrinsic-viscosity polyphenyl ether 北京赛福瑞技术服务有限公司 2024-03-29 CN disclosed
CN-116969816-A Bisphenol compound and double-end hydroxyl low molecular weight polyphenyl ether 北京赛福瑞技术服务有限公司 2023-10-31 CN disclosed
US-4385168-A FROM OXIDATIVE POLYMERIZATION OF PHENOLIC MONOMER IN PRESENCE OF MANGANIUM SALT AND HYDROXYAZO AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-24 US disclosed
EP-0059958-A1 Process for producing polyphenylene oxide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-09-15 EP disclosed
US-4098846-A IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1978-07-04 US disclosed
US-4054553-A MANGANESE COMPLEX CATALYST GENERAL ELECTRIC COMPANY (US) 1977-10-18 US disclosed
US-3972851-A Preparation of polyphenylene oxide using a manganese(II) ortho-hydroxyarene-oxime chelate reaction promoter GENERAL ELECTRIC COMPANY (US) 1976-08-03 US disclosed
US-3965069-A Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst GENERAL ELECTRIC COMPANY (US) 1976-06-22 US disclosed
US-3956242-A Preparation of polyphenylene oxide using a manganese (II) ω-hydroxyoxime chelate reaction promoter GENERAL ELECTRIC COMPANY (US) 1976-05-11 US disclosed