Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.37 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31291969 | 0.92 | FPR2 (0.50) | F2F10PRSS1FPR2GAA | |
| SCHEMBL33525505 | 0.91 | FPR2 (0.46) | F2F10PRSS1FPR2GAA | |
| SCHEMBL12185691 | 0.91 | FPR2 (0.46) | F2F10PRSS1FPR2GAA | |
| SCHEMBL13675582 | 0.91 | FPR2 (0.49) | F2F10PRSS1FPR2GAA | |
| SCHEMBL13399243 | 0.91 | FPR2 (0.46) | F2F10PRSS1FPR2GAA | |
| SCHEMBL33525685 | 0.91 | FPR2 (0.46) | F2F10PRSS1FPR2GAA | |
| SCHEMBL33525732 | 0.85 | FPR2 (0.51) | F2F10PRSS1FPR2GAA | |
| SCHEMBL2456099 | 0.82 | GAA (0.46) | F2F10PRSS1GAABTK | |
| SCHEMBL5637239 | 0.82 | GAA (0.46) | F2F10PRSS1GAABTK | |
| SCHEMBL2456097 | 0.82 | GAA (0.46) | F2F10PRSS1GAABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133336-A1 | STAT MODULATORS AND USES THEREOF | RECLUDIX PHARMA, INC. (US) | 2023-07-13 | — | — | WO | disclosed |