Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665646 | 0.79 | CYP3A4 (0.45) | IDH1CYP3A4CYP2C9SLC22A6SLC22A8 | |
| SCHEMBL19091527 | 0.78 | TRPA1 (0.53) | TRPA1ARKCNH3IDH2XPO1 | |
| Hydrochloric Acid SCHEMBL28527606 | 0.77 | CYP3A4 (0.44) | IDH1CYP3A4CYP2C9SLC22A6SLC22A8 | |
| SCHEMBL28111054 | 0.75 | AR (0.52) | CYP3A4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL10690353 | 0.75 | CYP3A4 (0.45) | IDH1CYP3A4CYP2C9SLC22A6SLC22A8 | |
| SCHEMBL11900495 | 0.75 | CYP3A4 (0.45) | CYP3A4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL24782865 | 0.74 | CYP3A4 (0.42) | CYP3A4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL18477982 | 0.72 | TDP1 (0.38) | CYP3A4SLC22A12GPR55KCNH3ALDH1A1 | |
| SCHEMBL3749196 | 0.72 | CYP11B1 (0.43) | CYP3A4CYP2C9SLC22A6SLC22A8SLC22A12 | |
| SCHEMBL633235 | 0.72 | CA12 (0.58) | CYP3A4CYP2C9TRPA1KMT2AIDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | UNIV YALE (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | ASGR1, LDLR, FCGR2A | IDH1 2469/4885CYP3A4 2670/4885CYP2C9 2381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.