Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18409776 | 0.86 | KCNN4 (0.49) | HTTKIF11KCNH2KCNN4LTA4H | |
| SCHEMBL9439820 | 0.85 | KIF11 (0.47) | HTTKDM4EMEN1KMT2AKIF11 | |
| SCHEMBL5391076 | 0.85 | KIF11 (0.61) | KIF11KCNH2KCNN4DRD2DRD4 | |
| SCHEMBL4363002 | 0.83 | KIF11 (0.49) | HTTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL12225852 | 0.83 | KIF11 (0.49) | HTTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL10071078 | 0.83 | KIF11 (0.49) | HTTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6302955 | 0.82 | KIF11 (0.45) | HTTKDM4EMEN1KMT2AKIF11 | |
| SCHEMBL8053146 | 0.82 | KIF11 (0.45) | HTTKDM4EMEN1KMT2AKIF11 | |
| SCHEMBL8040236 | 0.82 | KIF11 (0.44) | HTTKIF11KCNH2KCNN4LTA4H | |
| SCHEMBL10309879 | 0.82 | KIF11 (0.45) | HTTKDM4EMEN1KMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906246-B1 | VEGF NEUTRALIZING PRODRUGS COMPRISING RANIBIZUMAB FOR THE TREATMENT OF OCULAR CONDITIONS CHARACTERIZED BY OCULAR NEOVASCULARIZATION | ASCENDIS PHARMA OPHTHALMOLOGY DIV A/S (DK) | 2023-07-26 | — | — | EP | disclosed |