SCHEMBL25869419

SCHEMBL25869419

CCCCCCCCCCCCOCC(CN(CCOCc1ccccc1)C1CCC1)OCCCCCCCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 10/20 0.42
PLA2G2A P14555 4/20 0.41
PLA2G10 O15496 2/20 0.41
PLA2G1B P04054 1/20 0.38
PLA2G5 P39877 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
POLB P06746 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR2 Q9HBW0 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25869415 0.88 POLB (0.46) L3MBTL1TDP1POLB
SCHEMBL25869430 0.86 TLR2 (0.43) TLR2
SCHEMBL25869422 0.85 PTPN1 (0.42) TLR2L3MBTL1
SCHEMBL25869429 0.85 PTPN1 (0.42) TLR2L3MBTL1
SCHEMBL25078776 0.80 PLA2G10 (0.55) TLR2PLA2G2APLA2G10PLA2G1BPLA2G5
SCHEMBL6811774 0.80 PLA2G10 (0.55) TLR2PLA2G2APLA2G10PLA2G1BPLA2G5
SCHEMBL6813208 0.80 PLA2G10 (0.55) TLR2PLA2G2APLA2G10PLA2G1BPLA2G5
SCHEMBL4368865 0.80 PLA2G10 (0.55) TLR2PLA2G2APLA2G10PLA2G1BPLA2G5
SCHEMBL2411920 0.80 PLA2G10 (0.55) TLR2PLA2G2APLA2G10PLA2G1BPLA2G5
SCHEMBL3762356 0.80 PLA2G10 (0.55) TLR2PLA2G2APLA2G10PLA2G1BPLA2G5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-07-27 US disclosed
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS CETP, NPC1, LCAT TLR2 1063/4885PLA2G2A 265/4885PLA2G10 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.