SCHEMBL25869429

SCHEMBL25869429

CCCCCCCCCCCCOCC(CN(CCOCc1ccccc1)C1CCC1)OC(=O)CCCCC

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.42
EPHX2 P34913 1/20 0.40
CNR2 P34972 6/20 0.40
CNR1 P21554 4/20 0.40
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
TLR2 O60603 2/20 0.39
PRKCA P17252 1/20 0.38
PRKCE Q02156 1/20 0.38
PRKCQ Q04759 1/20 0.38
PRKCD Q05655 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25869422 1.00 PTPN1 (0.42) PTPN1EPHX2CNR2CNR1MAPT
SCHEMBL25873835 0.86 TLR2 (0.41) PTPN1CNR2CNR1MAPTMAPK1
SCHEMBL25874010 0.86 TLR2 (0.41) PTPN1CNR2CNR1MAPTMAPK1
SCHEMBL25869430 0.85 TLR2 (0.43) PTPN1TLR2
SCHEMBL25869419 0.85 TLR2 (0.42) TLR2L3MBTL1
SCHEMBL25873822 0.84 L3MBTL1 (0.41) CNR2CNR1TLR2L3MBTL1ALDH1A1
SCHEMBL25873598 0.84 TLR2 (0.36) TLR2
SCHEMBL25869415 0.84 POLB (0.46) MAPK1L3MBTL1LMNA
SCHEMBL24968265 0.83 MAPT (0.50) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL24968269 0.83 MAPT (0.50) MAPTMAPK1PRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-07-27 US disclosed
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS CETP, NPC1, LCAT PTPN1 2202/4885EPHX2 2210/4885CNR2 4517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.