SCHEMBL25869497

SCHEMBL25869497

CCCCCCCCCCCCOCC(O)CNCCN(CC)CC

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.54
USP2 O75604 1/20 0.51
LPAR5 Q9H1C0 4/20 0.44
SPHK1 Q9NYA1 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 1/20 0.41
PLA2G2C Q5R387 2/20 0.39
CASR P41180 1/20 0.38
LMNA P02545 1/20 0.36
TLR2 O60603 2/20 0.36
LPAR1 Q92633 5/20 0.35
LPAR3 Q9UBY5 5/20 0.35
LPAR2 Q9HBW0 4/20 0.35
LPAR6 P43657 3/20 0.35
LPAR4 Q99677 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13828867 0.86 USP2 (0.51) HTTUSP2LPAR5SPHK1CYP1A2
SCHEMBL12515791 0.86 USP2 (0.51) HTTUSP2LPAR5SPHK1CYP1A2
SCHEMBL15393759 0.85 USP2 (0.61) HTTUSP2LPAR5SPHK1CYP1A2
SCHEMBL21019381 0.85 USP2 (0.61) HTTUSP2LPAR5SPHK1CYP1A2
SCHEMBL11238943 0.82 HTT (0.65) HTTUSP2LPAR5SPHK1CYP1A2
SCHEMBL11223752 0.82 HTT (0.65) HTTUSP2LPAR5SPHK1CYP1A2
SCHEMBL11231700 0.82 HTT (0.65) HTTUSP2LPAR5SPHK1CYP1A2
SCHEMBL5533039 0.82 USP2 (0.62) HTTUSP2LPAR5SPHK1CYP1A2
SCHEMBL314577 0.82 USP2 (0.62) HTTUSP2LPAR5SPHK1CYP1A2
SCHEMBL13269710 0.82 USP2 (0.62) HTTUSP2LPAR5SPHK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-07-27 US disclosed
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233468-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS CETP, NPC1, LCAT HTT 959/4885USP2 2151/4885LPAR5 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.