Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.35 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.35 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515791 | 1.00 | USP2 (0.51) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL8453588 | 0.87 | USP2 (0.60) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL25869497 | 0.86 | HTT (0.54) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL8457923 | 0.85 | USP2 (0.62) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL3924210 | 0.85 | USP2 (0.62) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL314577 | 0.85 | USP2 (0.62) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL5533039 | 0.85 | USP2 (0.62) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL13269710 | 0.85 | USP2 (0.62) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL21019381 | 0.85 | USP2 (0.61) | USP2HTTLPAR5SPHK1CYP1A2 | |
| SCHEMBL12886458 | 0.85 | USP2 (0.56) | USP2HTTLPAR5SPHK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9080186-B2 | Compositions comprising cationic amphiphiles and colipids for delivering therapeutic molecules | AGAVE PHARMA, INCORPORATED (US) | 2015-07-14 | — | — | US | disclosed |
| US-9080186-B2 | Compositions comprising cationic amphiphiles and colipids for delivering therapeutic molecules | AGAVE PHARMA, INCORPORATED (US) | 2015-07-14 | — | — | US | disclosed |
| US-20120289584-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND COLIPIDS FOR DELIVERING THERAPEUTIC MOLECULES | AGAVE PHARMA, INCORPORATED (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120289584-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND COLIPIDS FOR DELIVERING THERAPEUTIC MOLECULES | AGAVE PHARMA, INCORPORATED (US) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289584-A1 | COMPOSITIONS COMPRISING CATIONIC AMPHIPHILES AND COLIPIDS FOR DELIVERING THERAPEUTIC MOLECULES | ANXA4, ANXA6, RNASE1 | USP2 3440/4885HTT 473/4885LPAR5 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.