Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 12/20 | 0.75 |
| ▸ | EGFR | P00533 | 8/20 | 0.71 |
| ▸ | MET | P08581 | 1/20 | 0.60 |
| ▸ | INSR | P06213 | 2/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | ROS1 | P08922 | 1/20 | 0.59 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25869943 | 0.93 | EGFR (0.73) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25872148 | 0.93 | ALK (0.73) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25871548 | 0.91 | ALK (0.65) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25871745 | 0.90 | ALK (0.61) | ALKEGFRMETINSRAURKA | |
| SCHEMBL29059835 | 0.90 | ALK (0.76) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25870035 | 0.89 | EGFR (0.72) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25872849 | 0.88 | ALK (0.59) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25306773 | 0.88 | EGFR (0.77) | ALKEGFRMET | |
| SCHEMBL29059803 | 0.88 | ALK (0.62) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25874808 | 0.86 | EGFR (0.64) | ALKEGFRMETINSRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212522-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H Biotech Inc. (KR) | 2023-07-19 | — | — | EP | disclosed |