Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 13/20 | 0.73 |
| ▸ | EGFR | P00533 | 8/20 | 0.62 |
| ▸ | MET | P08581 | 1/20 | 0.56 |
| ▸ | INSR | P06213 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ROS1 | P08922 | 1/20 | 0.55 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25869800 | 0.93 | ALK (0.75) | ALKEGFRMETINSRAURKA | |
| SCHEMBL29059674 | 0.91 | ALK (0.74) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25299463 | 0.89 | ALK (0.72) | ALKEGFRMET | |
| SCHEMBL25872232 | 0.88 | ALK (0.59) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25869943 | 0.88 | EGFR (0.73) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25308115 | 0.87 | ALK (0.71) | ALKEGFRMETINSR | |
| SCHEMBL25872145 | 0.87 | ALK (0.66) | ALKEGFR | |
| SCHEMBL25871548 | 0.86 | ALK (0.65) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25871745 | 0.86 | ALK (0.61) | ALKEGFRMETINSRAURKA | |
| SCHEMBL25870035 | 0.85 | EGFR (0.72) | ALKEGFRMETINSRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212522-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H Biotech Inc. (KR) | 2023-07-19 | — | — | EP | disclosed |