Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 7/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834732 | 1.00 | MEN1 (0.46) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL27330974 | 1.00 | MEN1 (0.46) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL26031865 | 0.98 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13616087 | 0.92 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL20466149 | 0.91 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL25851509 | 0.91 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL20466152 | 0.91 | MEN1 (0.44) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL25836519 | 0.91 | TSHR (0.44) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL11912095 | 0.88 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL21029891 | 0.88 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |