Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | TET3 | O43151 | 5/20 | 0.43 |
| ▸ | FBXL19 | Q6PCT2 | 5/20 | 0.43 |
| ▸ | CXXC5 | Q7LFL8 | 5/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.43 |
| ▸ | CXXC4 | Q9H2H0 | 5/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.43 |
| ▸ | TET1 | Q8NFU7 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854333 | 0.88 | HRH3 (0.46) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL3469565 | 0.85 | HRH3 (0.44) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL29829152 | 0.80 | KMT2A (0.47) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL23366023 | 0.79 | CHRNA7 (0.45) | HRH3CYP2D6KCNH2 | |
| SCHEMBL24918193 | 0.78 | CYP2C9 (0.57) | KMT2AHRH3CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL16375283 | 0.77 | KMT2A (0.40) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL23811145 | 0.77 | KMT2A (0.45) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL24918399 | 0.77 | CYP2D6 (0.41) | HRH3CYP2D6CYP2C9CYP3A4ALDH1A1 | |
| SCHEMBL16375288 | 0.76 | HRH3 (0.41) | KMT2AHRH3CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL16375286 | 0.75 | JAK3 (0.38) | KMT2ATET3FBXL19CXXC5KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |