Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 14/20 | 0.56 |
| ▸ | INSR | P06213 | 3/20 | 0.55 |
| ▸ | IGF1R | P08069 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.52 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.52 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870490 | 0.92 | ALK (0.58) | ALKINSRIGF1REGFRMAP3K7 | |
| SCHEMBL26497839 | 0.91 | EGFR (0.63) | ALKINSRIGF1REGFRMAP3K7 | |
| SCHEMBL30497501 | 0.91 | EGFR (0.63) | ALKINSRIGF1REGFRMAP3K7 | |
| SCHEMBL29059663 | 0.90 | ALK (0.57) | ALKINSRIGF1REGFRMAP3K7 | |
| SCHEMBL25869799 | 0.86 | ALK (0.75) | ALKINSRIGF1REGFRZAP70 | |
| SCHEMBL25871301 | 0.86 | EGFR (0.63) | ALKINSRIGF1REGFRMAP3K7 | |
| SCHEMBL25870243 | 0.86 | EGFR (0.61) | ALKINSRIGF1REGFRMAP3K7 | |
| SCHEMBL25871972 | 0.85 | ALK (0.57) | ALKINSRIGF1REGFRMAP3K7 | |
| SCHEMBL25872847 | 0.85 | ALK (0.63) | ALKINSRIGF1REGFRZAP70 | |
| SCHEMBL25870332 | 0.85 | ALK (0.60) | ALKINSRIGF1REGFRMAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212522-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H Biotech Inc. (KR) | 2023-07-19 | — | — | EP | disclosed |