Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 16/20 | 0.60 |
| ▸ | INSR | P06213 | 4/20 | 0.60 |
| ▸ | IGF1R | P08069 | 4/20 | 0.60 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870244 | 0.94 | EGFR (0.64) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL25870490 | 0.90 | ALK (0.58) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL25304856 | 0.90 | EGFR (0.69) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL25871302 | 0.90 | EGFR (0.66) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL25870243 | 0.86 | EGFR (0.61) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL25871978 | 0.86 | ALK (0.60) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL29059883 | 0.85 | ALK (0.62) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL25871927 | 0.85 | ALK (0.62) | ALKINSRIGF1REGFRMET | |
| SCHEMBL29059803 | 0.85 | ALK (0.62) | ALKINSRIGF1RMAP3K7EGFR | |
| SCHEMBL25872232 | 0.85 | ALK (0.59) | ALKINSRIGF1RMAP3K7EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212522-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H Biotech Inc. (KR) | 2023-07-19 | — | — | EP | disclosed |