Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 12/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.36 |
| ▸ | MEN1 | O00255 | 10/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18863387 | 0.95 | CISD1 (0.39) | CISD1MAOBMAPTKMT2AMEN1 | |
| SCHEMBL18863386 | 0.94 | MAPT (0.39) | MAPTKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL18863393 | 0.83 | MAPT (0.40) | CISD1MAOBMAPTKMT2AMEN1 | |
| SCHEMBL28703551 | 0.79 | CISD1 (0.32) | CISD1MAOB | |
| SCHEMBL28705801 | 0.78 | NOX4 (0.31) | NOX4NOX1 | |
| SCHEMBL18882576 | 0.76 | KMT2A (0.44) | CISD1MAOBMAPTKMT2AMEN1 | |
| SCHEMBL19652004 | 0.75 | MAPT (0.63) | MAPTKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL18863392 | 0.72 | MAPT (0.33) | CISD1MAOBMAPTKMT2AMEN1 | |
| SCHEMBL18882628 | 0.70 | KMT2A (0.47) | CISD1MAOBMAPTKMT2AMEN1 | |
| SCHEMBL18882565 | 0.69 | MAPT (0.43) | MAPTKMT2AMEN1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11711930-B2 | — | — | 2023-07-25 | — | — | US | disclosed |