Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.36 |
| ▸ | MAOB | P27338 | 8/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13016 | 0.91 | NPC1 (0.50) | NPC1RAB9AMAPTAPPLMNA | |
| Iodide SCHEMBL5175074 | 0.89 | NPC1 (0.48) | NPC1RAB9AMAPTAPPLMNA | |
| SCHEMBL20674280 | 0.83 | TAAR1 (0.50) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL24555477 | 0.81 | NPC1 (0.43) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL779443 | 0.81 | NPC1 (0.58) | NPC1RAB9AMAPTLMNAMAPK1 | |
| Sulfuric Acid SCHEMBL2773087 | 0.79 | NPC1 (0.43) | NPC1RAB9AMAPTAPPLMNA | |
| Sulfuric Acid SCHEMBL2773086 | 0.79 | NPC1 (0.43) | NPC1RAB9AMAPTAPPLMNA | |
| SCHEMBL24555478 | 0.76 | NPC1 (0.40) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL12967599 | 0.75 | NPC1 (0.48) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL26844942 | 0.75 | ESR1 (0.45) | NPC1RAB9AMAPTAPPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230235177-A1 | Deep Ultraviolet-Excitable Water-Solvated Polymeric Dyes | BECTON, DICKINSON AND COMPANY | 2023-07-27 | — | — | US | disclosed |