Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22455919 | 0.87 | MAPT (0.60) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL10153002 | 0.87 | GAA (0.64) | MAPTALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL25442201 | 0.85 | MAPT (0.52) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL22455933 | 0.85 | ALDH1A1 (0.55) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL25442202 | 0.84 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL25442200 | 0.81 | MAPT (0.43) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL20279143 | 0.80 | ALDH1A1 (0.50) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL8794400 | 0.80 | ALDH1A1 (0.69) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL20279747 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL15071215 | 0.79 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | AUTOTAC INC. (KR) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | UBR4, UBQLN2, UBTF | MAPT 235/4885ALDH1A1 2317/4885CYP1A2 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.