SCHEMBL25870909

SCHEMBL25870909

Cc1ccc(S(=O)(=O)NNC(=O)c2ccc(O)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.78
KMT2A Q03164 5/20 0.78
L3MBTL1 Q9Y468 1/20 0.78
KDM4E B2RXH2 1/20 0.72
MEN1 O00255 2/20 0.71
POLB P06746 3/20 0.69
TDP1 Q9NUW8 3/20 0.67
HPGD P15428 2/20 0.67
KAT6A Q92794 3/20 0.66
LMNA P02545 3/20 0.65
GFER P55789 1/20 0.63
MAPT P10636 1/20 0.62
ALDH1A1 P00352 2/20 0.58
BCAT1 P54687 1/20 0.57
RAB9A P51151 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7151474 0.87 KAT6A (0.78) GAAKMT2AL3MBTL1KDM4EMEN1
SCHEMBL25872681 0.87 KMT2A (0.71) GAAKMT2AL3MBTL1KDM4EMEN1
SCHEMBL25241197 0.84 KMT2A (0.71) GAAKMT2AL3MBTL1KDM4EMEN1
SCHEMBL25872106 0.84 KMT2A (0.71) GAAKMT2AL3MBTL1KDM4EMEN1
SCHEMBL26104327 0.83 MEN1 (1.00) GAAKMT2AMEN1KAT6ABCAT1
SCHEMBL25872083 0.83 GFER (0.91) GAAKMT2AL3MBTL1MEN1KAT6A
SCHEMBL25872786 0.83 KMT2A (0.69) GAAKMT2AL3MBTL1KDM4EMEN1
SCHEMBL25872095 0.81 KMT2A (0.68) GAAKMT2AL3MBTL1KDM4EMEN1
SCHEMBL25288758 0.81 KMT2A (0.62) GAAKMT2AL3MBTL1KDM4EMEN1
SCHEMBL25872350 0.80 GAA (0.80) GAAKMT2AMEN1POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115715285-A Compounds as UBR box domain ligands 奧土择破利悟 2023-02-24 CN claimed
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed
CN-115715285-A Compounds as UBR box domain ligands 奧土择破利悟 2023-02-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND UBR4, UBQLN2, UBTF GAA 996/4885KMT2A 1391/4885L3MBTL1 1141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.