Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23542105 | 0.83 | KMT2A (0.60) | MEN1KMT2AALDH1A1SMN1; SMN2TACR3 | |
| SCHEMBL21777490 | 0.80 | MEN1 (0.61) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL25312202 | 0.77 | KMT2A (0.54) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9004208 | 0.75 | CASR (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2AOC3 | |
| SCHEMBL4234045 | 0.75 | KMT2A (0.48) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL30264834 | 0.75 | KMT2A (0.48) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15811721 | 0.75 | KMT2A (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL25327103 | 0.73 | S1PR3 (0.46) | MEN1KMT2A | |
| SCHEMBL25327106 | 0.73 | S1PR3 (0.46) | MEN1KMT2A | |
| SCHEMBL1712790 | 0.73 | KMT2A (0.49) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137634-A1 | TRICYCLIC COMPOUND, PREPARATION THEREFOR, PHARMACEUTICAL COMPOSITION AND USE | 上海奕拓医药科技有限责任公司 | 2023-07-27 | — | — | WO | disclosed |