Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 14/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602212 | 0.79 | NOTUM (0.61) | NAMPTNOTUMTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3705406 | 0.77 | NAMPT (1.00) | NAMPT | |
| SCHEMBL10226370 | 0.76 | NPC1 (0.78) | NAMPTTAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL24815812 | 0.76 | NAMPT (0.73) | NAMPT | |
| SCHEMBL29986834 | 0.76 | NAMPT (0.73) | NAMPT | |
| SCHEMBL29728593 | 0.76 | NOTUM (0.61) | NAMPTNOTUMTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3704956 | 0.76 | NOTUM (0.61) | NAMPTNOTUMTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL27724288 | 0.75 | NOTUM (0.67) | NAMPTNOTUMTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17169484 | 0.75 | NOTUM (0.55) | NAMPTNOTUMTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL26257474 | 0.75 | NAMPT (0.67) | NAMPTNOTUMTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | AUTOTAC INC. (KR) | 2023-06-08 | — | — | US | disclosed |
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | AUTOTAC INC. (KR) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174470-A1 | COMPOUND AS A UBR BOX DOMAIN LIGAND | UBR4, UBQLN2, UBTF | NAMPT 4319/4885NOTUM 4415/4885TAS1R3 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.