SCHEMBL2587121

SCHEMBL2587121

COc1ccccc1-c1cccc(CC(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 2/20 0.62
SELP P16109 2/20 0.62
FFAR1 O14842 4/20 0.61
HTR7 P34969 5/20 0.61
PTGER1 P34995 1/20 0.56
PTGER4 P35408 1/20 0.56
PTGER3 P43115 1/20 0.56
PTGER2 P43116 1/20 0.56
PTPN5 P54829 1/20 0.52
GAA P10253 2/20 0.51
ALDH1A1 P00352 1/20 0.51
TSHR P16473 1/20 0.51
NFKB1 P19838 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
PLA2G10 O15496 1/20 0.50
PLA2G2A P14555 1/20 0.50
CTSA P10619 2/20 0.49
SELE P16581 1/20 0.49
PPARG P37231 1/20 0.49
PPARA Q07869 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7031826 0.87 HTR7 (0.63) SELLSELPFFAR1HTR7PTGER1
SCHEMBL21368940 0.87 HTR7 (0.59) SELLSELPFFAR1HTR7PTPN5
SCHEMBL3670702 0.86 FFAR1 (0.76) FFAR1HTR7PTGER1PTGER4PTGER3
SCHEMBL4172402 0.85 CYP1A1 (0.63) SELLSELPFFAR1GAAALDH1A1
SCHEMBL17187933 0.84 PLA2G10 (0.60) SELLSELPFFAR1PTGER1PTGER4
SCHEMBL2592720 0.83 HTR7 (0.56) SELLSELPFFAR1HTR7PTPN5
SCHEMBL4207640 0.83 SLC13A5 (0.60) FFAR1PTGER4GAAALDH1A1TSHR
SCHEMBL3839813 0.82 PLA2G10 (0.58) SELLSELPPTGER1PTGER4PTGER3
SCHEMBL20519924 0.82 GAA (0.62) SELLSELPGAAALDH1A1TSHR
SCHEMBL28454360 0.82 GAA (0.62) SELLSELPGAAALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2566580-A1 PROCESS FOR THE PREPARATION OF BIMOSIAMOSE Revotar Biopharmaceuticals AG (DE) 2013-03-13 EP claimed
WO-2011138365-A1 PROCESS FOR THE PREPARATION OF BIMOSIAMOSE REVOTAR BIOPHARMACEUTICALS AG (DE) 2011-11-10 WO claimed
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS SERVIER LAB (FR) 2026-01-01 US disclosed
EP-4551566-A1 NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS Les Laboratoires Servier (FR) 2025-05-14 EP disclosed
WO-2024008941-A1 NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS LES LABORATOIRES SERVIER (FR) 2024-01-11 WO disclosed
CN-103002951-A Process for the preparation of new compound REVOTAR BIOPHARMACEUTICALS AG 2013-03-27 CN disclosed
EP-2566580-A1 PROCESS FOR THE PREPARATION OF BIMOSIAMOSE Revotar Biopharmaceuticals AG (DE) 2013-03-13 EP disclosed
EP-2566580-A1 PROCESS FOR THE PREPARATION OF BIMOSIAMOSE Revotar Biopharmaceuticals AG (DE) 2013-03-13 EP disclosed
WO-2011138365-A1 PROCESS FOR THE PREPARATION OF BIMOSIAMOSE REVOTAR BIOPHARMACEUTICALS AG (DE) 2011-11-10 WO disclosed
WO-2011138365-A1 PROCESS FOR THE PREPARATION OF BIMOSIAMOSE REVOTAR BIOPHARMACEUTICALS AG (DE) 2011-11-10 WO disclosed
US-5444050-A Binding of E-selectin or P-selectin to sialyl Lewisx or sialyl-Lewisa TEXAS BIOTECHNOLOGY CORPORATION (US) 1995-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001846-A1 SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS BCL2, BCL2A1, BAX SELL 3703/4885SELP 3242/4885FFAR1 600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.