Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793891 | 1.00 | IDO1 (0.61) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL16382293 | 0.85 | IDO1 (0.73) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL31408101 | 0.85 | IDO1 (0.73) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17361199 | 0.85 | CYP3A4 (0.54) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28832456 | 0.82 | CYP3A4 (0.51) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28084075 | 0.82 | CYP3A4 (0.53) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30538057 | 0.81 | CYP3A4 (0.41) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8469809 | 0.79 | IDO1 (0.66) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28287055 | 0.79 | IDO1 (0.66) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28484926 | 0.78 | IDO1 (0.63) | IDO1CYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484453-A | Derivatives of imidazo [1, 2-alpha ] pyridine-2-carboxamides, their preparation and their use in therapy | SANOFI AVENTIS (FR) | 2009-07-15 | — | — | CN | claimed |
| EP-1228069-A2 | BICYCLIC AND TRICYCLIC HETEROAROMATIC COMPOUNDS | NEUROGEN CORPORATION (US) | 2002-08-07 | — | — | EP | claimed |
| WO-2001034603-A2 | BICYCLIC AND TRICYCLIC HETEROAROMATIC COMPOUNDS | NEUROGEN CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| EP-4329041-A1 | NON-AQUEOUS ELECTROLYTE COMPRISING ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, AND LITHIUM SECONDARY BATTERY COMPRISING SAME | LG Energy Solution, Ltd. (KR) | 2024-02-28 | — | — | EP | disclosed |
| WO-2023121028-A1 | NON-AQUEOUS ELECTROLYTE COMPRISING ADDITIVE FOR NON-AQUEOUS ELECTROLYTE, AND LITHIUM SECONDARY BATTERY COMPRISING SAME | 주식회사 엘지에너지솔루션 | 2023-06-29 | — | — | WO | disclosed |
| EP-3938364-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020186291-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2020-09-24 | — | — | WO | disclosed |
| CN-106699771-A | Cryptotanshinone compound, as well as preparation method and application thereof | 常州大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-103097384-B | Substituted imidazo [1,2-a ] pyrimidines and pyridines | 拜耳知识产权有限责任公司 | 2017-02-15 | — | — | CN | disclosed |
| EP-2595989-B1 | HETEROCYCLIC CHROMENE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS | VERTEX PHARMA (US) | 2016-07-13 | — | — | EP | disclosed |
| EP-2595989-B1 | HETEROCYCLIC CHROMENE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS | VERTEX PHARMA (US) | 2016-07-13 | — | — | EP | disclosed |
| CN-101074212-A | Diphenyl imidazole compound containing fluorine atom | DONGSHUO SCIENCE & TECHNOLOGY (CN) | 2007-11-21 | — | — | CN | disclosed |
| CN-101027075-A | Combination therapy for the treatment of obesity | MERCK & CO INC (US) | 2007-08-29 | — | — | CN | disclosed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4431815-A | CARDIOTONIC AND ANTISHOCK AGENTS; ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |