SCHEMBL25873126

SCHEMBL25873126

CCC(C)c1ccc(OC#N)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
TSHR P16473 2/20 0.49
GAA P10253 3/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC7A5 Q01650 1/20 0.40
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
HPGD P15428 3/20 0.39
CYP2C9 P11712 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSP90AA1 P07900 1/20 0.38
USP2 O75604 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5072879 0.82 CYP17A1 (0.45) ALDH1A1TSHRGAASMN1; SMN2
SCHEMBL15224747 0.81 PBRM1 (0.37) ALDH1A1TSHRGAA
SCHEMBL9346982 0.81 ESR1 (0.52) ALDH1A1MEN1KMT2ACYP2C9CYP1A2
SCHEMBL22966345 0.81 ESR1 (0.33) ALDH1A1TSHRGAA
SCHEMBL17042604 0.81 ESR1 (0.52) ALDH1A1MEN1KMT2ACYP2C9CYP1A2
SCHEMBL27939093 0.81 ESR1 (0.36) ALDH1A1TSHRGAAMAPTTDP1
SCHEMBL11300541 0.81 ALDH1A1 (0.53) ALDH1A1TSHRGAAMAPTTDP1
SCHEMBL139926 0.79 ESR1 (0.41) ALDH1A1GAASMN1; SMN2CYP1A2
SCHEMBL29913553 0.79 ESR1 (0.39) ALDH1A1GAASMN1; SMN2CYP1A2
SCHEMBL27657818 0.79 MEN1 (0.38) ALDH1A1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016699-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INC (US) 2024-01-18 US disclosed
US-11707411-B2 Pharmaceutical packages with coatings comprising polycyanurates CORNING INCORPORATED (US) 2023-07-25 US disclosed