SCHEMBL258735

SCHEMBL258735

CSCCC(NF)C(=O)N(C(=O)C(N)CC(C)C)C(Cc1ccccc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.44
RNPEP Q9H4A4 1/20 0.44
DNPEP Q9ULA0 1/20 0.44
FNTA P49354 5/20 0.42
FNTB P49356 5/20 0.42
PGGT1B P53609 4/20 0.42
LTA4H P09960 2/20 0.42
TACR3 P29371 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1128048 0.89 ANPEP (0.50) ANPEPRNPEPDNPEPFNTAFNTB
SCHEMBL61200 0.89 ANPEP (0.43) ANPEPRNPEPDNPEPFNTAFNTB
Acetic Acid SCHEMBL15201184 0.87 ANPEP (0.48) ANPEPRNPEPDNPEPFNTAFNTB
SCHEMBL1695338 0.81 FOLH1 (0.39) ANPEPRNPEPDNPEPFNTAFNTB
SCHEMBL27468737 0.77 ANPEP (0.53) ANPEPRNPEPDNPEPLTA4H
SCHEMBL7999637 0.77 ANPEP (0.51) ANPEPRNPEPDNPEPLTA4H
SCHEMBL28194148 0.77 ANPEP (0.42) ANPEPRNPEPDNPEPFNTAFNTB
SCHEMBL9242775 0.76 ANPEP (0.43) ANPEPRNPEPDNPEPLTA4H
SCHEMBL19974077 0.75 ANPEP (0.51) ANPEPRNPEPDNPEPLTA4H
SCHEMBL39530 0.74 ANPEP (0.37) ANPEPRNPEPDNPEPFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865857-B2 Medical device with predefined activated cellular integration SOFRADIM PRODUCTION (FR) 2014-10-21 US claimed
US-4732155-A Implantable chemoattractant system THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1988-03-22 US claimed
US-8865857-B2 Medical device with predefined activated cellular integration SOFRADIM PRODUCTION (FR) 2014-10-21 US disclosed
US-20130143976-A1 MEDICAL DEVICE WITH PREDEFINED ACTIVATED CELLULAR INTEGRATION SOFRADIM PRODUCTION (FR) 2013-06-06 US disclosed
EP-2588153-A2 MEDICAL DEVICE WITH PREDEFINED ACTIVATED CELLULAR INTEGRATION Sofradim Production (FR) 2013-05-08 EP disclosed
WO-2012001532-A2 MEDICAL DEVICE WITH PREDEFINED ACTIVATED CELLULAR INTEGRATION SOFRADIM PRODUCTION (FR) 2012-01-05 WO disclosed
US-20030138432-A1 Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs DRUG INNOVATION & DESIGN, INC. 2003-07-24 US disclosed
EP-1255567-A1 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES Drug Innovation & Design, Inc. (US) 2002-11-13 EP disclosed
WO-2001036003-A2 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES DRUG INNOVATION & DESIGN, INC. (US) 2001-05-25 WO disclosed
US-4732155-A Implantable chemoattractant system THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1988-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130143976-A1 MEDICAL DEVICE WITH PREDEFINED ACTIVATED CELLULAR INTEGRATION CCL2, MIF, C3AR1 ANPEP 741/4885RNPEP 904/4885DNPEP 656/4885
US-20030138432-A1 Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs PAICS, ABCB1, ABCG2 ANPEP 1636/4885RNPEP 1962/4885DNPEP 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.