SCHEMBL39530

SCHEMBL39530

CSCCC(N)C(=O)N(C(=O)C(N)CC(C)C)C(Cc1ccccc1C=O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.37
RNPEP Q9H4A4 1/20 0.37
DNPEP Q9ULA0 1/20 0.37
KRAS P01116 1/20 0.35
MARS1 P56192 2/20 0.33
FNTA P49354 4/20 0.32
FNTB P49356 4/20 0.32
PGGT1B P53609 2/20 0.32
CTSC P53634 2/20 0.32
LTA4H P09960 1/20 0.31
TACR3 P29371 1/20 0.31
LARS1 Q9P2J5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29045686 0.88 ANPEP (0.41) ANPEPRNPEPDNPEPLTA4HLARS1
SCHEMBL4398840 0.87 ANPEP (0.38) ANPEPRNPEPDNPEPLTA4HLARS1
SCHEMBL1128048 0.84 ANPEP (0.50) ANPEPRNPEPDNPEPKRASFNTA
Acetic Acid SCHEMBL15201184 0.83 ANPEP (0.48) ANPEPRNPEPDNPEPKRASFNTA
SCHEMBL9387444 0.80 ANPEP (0.39) ANPEPRNPEPDNPEPLTA4HLARS1
SCHEMBL7031217 0.79 MARS1 (0.36) KRASMARS1FNTAFNTBPGGT1B
SCHEMBL154435 0.77 FNTA (0.34) ANPEPRNPEPDNPEPKRASMARS1
SCHEMBL61200 0.77 ANPEP (0.43) ANPEPRNPEPDNPEPFNTAFNTB
SCHEMBL28194148 0.77 ANPEP (0.42) ANPEPRNPEPDNPEPKRASFNTA
SCHEMBL7027416 0.76 FNTA (0.33) ANPEPRNPEPDNPEPKRASMARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 759 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11519923-B2 Analyte detection system and method SIEMENS HEALTHINEERS NEDERLAND B.V. (NL) 2022-12-06 US claimed
CN-109328302-B Analyte detection systems and methods 西门子医疗系统荷兰有限公司 2022-06-07 CN claimed
EP-3497445-B1 METHODS FOR MICROPATTERNING AND MICROPATTERNED DEVICES IST AUSTRIA INSTITUTE OF SCIENCE AND TECH AUSTRIA (AT) 2022-02-16 EP claimed
US-20200182894-A1 ANALYTE DETECTION SYSTEM AND METHOD SIEMENS HEALTHINEERS NEDERLAND B.V. (NL) 2020-06-11 US claimed
EP-3282254-B1 METHOD OF PRODUCING A DEVICE FOR GUIDED CELL ACTIVATION IST AUSTRIA INSTITUTE OF SCIENCE AND TECH AUSTRIA (AT) 2019-07-31 EP claimed
US-20190170744-A1 MICROPATTERNING ASSEMBLY, METHODS FOR MICROPATTERNING, AND MICROPATTERNED DEVICES IST AUSTRIA - INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA (AT) 2019-06-06 US claimed
EP-3472616-A1 ANALYTE DETECTION SYSTEM AND METHOD Koninklijke Philips N.V. (NL) 2019-04-24 EP claimed
CN-109328302-A Analyte detection system and method 皇家飞利浦有限公司 2019-02-12 CN claimed
EP-3282254-A1 DEVICE FOR GUIDED CELL ACTIVATION IST Austria (Institute of Science and Technology Austria) (AT) 2018-02-14 EP claimed
WO-2017220483-A1 ANALYTE DETECTION SYSTEM AND METHOD KONINKLIJKE PHILIPS N.V. (NL) 2017-12-28 WO claimed
WO-2006089106-A2 PHOSPHOINOSITIDE 3-KINASE INHIBITORS FOR INHIBITING LEUKOCYTE ACCUMULATION ICOS CORPORATION (US) 2006-08-24 WO claimed
US-20050054614-A1 Methods of inhibiting leukocyte accumulation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-03-10 US claimed
WO-2005016349-A1 METHODS OF INHIBITING LEUKOCYTE ACCUMULATION ICOS CORPORATION (US) 2005-02-24 WO claimed
US-6696276-B2 Vasopermeability-enhancing conjugates UNIVERSITY OF SOUTHERN CALIFORNIA 2004-02-24 US claimed
US-20030113872-A1 Vasopermeability-enhancing conjugates EPSTEIN ALAN L (US) 2003-06-19 US claimed
US-6524823-B2 Vasopermeability-enhancing conjugates THE UNIVERSITY OF SOUTHERN CALIFORNIA 2003-02-25 US claimed
US-6416965-B2 COMBINING COMPOUND WITH PHOSPHOLIPASE D(PLD), TREATING MIXTURE WITH PHOSPHATIDYLCHOLINE SO THAT CLEAVAGE REACTION BETWEEN PHOSPHATIDYLCHOLINE AND PLD CAN OCCUR, RESULTING IN GENERATION OF PHOSPHATIDIC ACID AND CHOLINE, EVALUATING AMOUNT OF CHOLINE BRIGHAM AND WOMEN'S HOSPITAL 2002-07-09 US claimed
US-20020068328-A1 Vasopermeability-enhancing conjugates UNIVERSITY OF SOUTHERN CALIFORNIA, THE 2002-06-06 US claimed
US-6007817-A Vasopermeability enhancing immunoconjugates UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1999-12-28 US claimed
EP-0438497-B1 VASOPERMEABILITY-ENHANCING CONJUGATES UNIV SOUTHERN CALIFORNIA (US) 1996-03-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054614-A1 Methods of inhibiting leukocyte accumulation PI4KB, PIK3CD, PIK3CA ANPEP 2747/4885RNPEP 2246/4885DNPEP 2225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.