SCHEMBL25874359

SCHEMBL25874359

CC(C)(C)c1nc2ccccc2n1-c1cccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc(-c5ccc(C#N)cc5)c4)n3)cc2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.42
CYP1A2 P05177 4/20 0.40
CYP3A4 P08684 3/20 0.40
MEN1 O00255 3/20 0.40
ALDH1A1 P00352 3/20 0.40
KMT2A Q03164 3/20 0.40
TSHR P16473 3/20 0.40
CYP2C19 P33261 2/20 0.40
CLK4 Q9HAZ1 2/20 0.40
CYP2D6 P10635 2/20 0.40
LMNA P02545 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP2C9 P11712 1/20 0.40
ADORA2A P29274 1/20 0.39
RPS6KB1 P23443 2/20 0.38
ABCG2 Q9UNQ0 9/20 0.38
MAPK1 P28482 1/20 0.38
ACSS2 Q9NR19 1/20 0.37
ABCB1 P08183 4/20 0.37
ALDH1A3 P47895 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875145 0.90 CYP1A2 (0.42) SLC22A12CYP1A2CYP3A4MEN1ALDH1A1
SCHEMBL25874524 0.90 SLC22A12 (0.43) SLC22A12CYP1A2CYP3A4MEN1ALDH1A1
SCHEMBL25875043 0.86 ALDH1A1 (0.45) MEN1ALDH1A1KMT2ALMNAHSD17B10
SCHEMBL25875035 0.84 CYP1A2 (0.40) SLC22A12CYP1A2CYP3A4MEN1ALDH1A1
SCHEMBL25878198 0.84 MAPK1 (0.46) SLC22A12ALDH1A1LMNAADORA2AMAPK1
SCHEMBL25874368 0.82 ALDH1A1 (0.38) MEN1ALDH1A1KMT2ALMNAHSD17B10
SCHEMBL25874911 0.82 SLC22A12 (0.43) SLC22A12TSHRCLK4LMNAADORA2A
SCHEMBL25874699 0.81 RPS6KB1 (0.43) SLC22A12CYP1A2CYP3A4MEN1ALDH1A1
SCHEMBL25874595 0.80 RPS6KB1 (0.43) SLC22A12CYP1A2CYP3A4MEN1ALDH1A1
SCHEMBL12679893 0.78 KDM4E (0.40) SLC22A12MEN1ALDH1A1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023140649-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-27 WO disclosed