Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.38 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25260366 | 0.79 | SMN1; SMN2 (0.49) | KDM4EALDH1A1HTTPOLBTDP1 | |
| SCHEMBL517399 | 0.78 | EGFR (0.45) | INSRIGF1RALK | |
| SCHEMBL30018553 | 0.78 | EGFR (0.45) | INSRIGF1RALK | |
| SCHEMBL10207156 | 0.78 | PDCD1 (0.41) | ALDH1A1L3MBTL1GAA | |
| SCHEMBL23759617 | 0.77 | HTR1A (0.44) | KDM4EALDH1A1HTTDRD2DRD3 | |
| SCHEMBL3122615 | 0.77 | CCR4 (0.42) | L3MBTL1 | |
| SCHEMBL30936906 | 0.76 | GAA (0.45) | KDM4EALDH1A1HTTGAAALOX12 | |
| SCHEMBL24204769 | 0.76 | GAA (0.45) | KDM4EALDH1A1HTTGAAALOX12 | |
| SCHEMBL23154031 | 0.76 | EGFR (0.41) | KDM4EALDH1A1HTTDRD2DRD3 | |
| SCHEMBL311360 | 0.75 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HTTTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212522-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H Biotech Inc. (KR) | 2023-07-19 | — | — | EP | disclosed |