SCHEMBL25875390

SCHEMBL25875390

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(-c4ccc5c(c4)C4(c6ccccc6-5)c5ccc6ccccc6c5Oc5c4ccc4ccccc54)cc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PDK2 Q15119 8/20 0.35
KIF11 P52732 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
FYN P06241 1/20 0.32
MAPK3 P27361 1/20 0.32
AHR P35869 1/20 0.32
PAX8 Q06710 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874824 0.94 PDK2 (0.35) KDM4EMAPTPDK2CYP1A2
SCHEMBL25875385 0.93 PDK2 (0.32) KMT2AKDM4EMEN1LMNAMAPT
SCHEMBL25876500 0.91 KIF11 (0.31) KMT2AKDM4EMEN1LMNAMAPT
SCHEMBL20387513 0.90 PDK2 (0.32) PDK2
SCHEMBL20387550 0.89 PDK2 (0.33) PDK2
SCHEMBL20387512 0.89 PDK2 (0.31) KMT2AKDM4EMEN1LMNAMAPT
SCHEMBL25864349 0.89 PDK2 (0.32) KMT2AKDM4EMEN1LMNAMAPT
SCHEMBL20387151 0.89 PDK2 (0.33) KMT2AKDM4EMEN1LMNAMAPT
SCHEMBL20926471 0.89 PDK2 (0.31) KMT2AKDM4EMEN1LMNAMAPT
SCHEMBL22095855 0.89 PDK2 (0.31) KMT2AKDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023120714-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-06-29 WO disclosed