SCHEMBL25875540

SCHEMBL25875540

CC(C)(O)C(C)(C)OBc1ccc(-c2ccccc2-c2ccccc2-c2ccc(-n3c(-c4ccccc4)nc4ccccc43)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.51
ESR1 P03372 4/20 0.51
GRIA1 P42261 1/20 0.45
CACNG8 Q8WXS5 1/20 0.45
CACNG2 Q9Y698 1/20 0.45
RECQL P46063 1/20 0.41
PTGS2 P35354 1/20 0.39
KDM4E B2RXH2 2/20 0.38
HSD17B10 Q99714 1/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
HPGD P15428 1/20 0.37
ALDH1A1 P00352 3/20 0.36
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
RAB9A P51151 2/20 0.36
SLC22A12 Q96S37 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18597398 0.94 ESR2 (0.57) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL17536059 0.92 ESR1 (0.51) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL15336505 0.91 ESR1 (0.50) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL12694195 0.82 ESR1 (0.49) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL24285646 0.79 ESR1 (0.39) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL24190999 0.78 CYP1A2 (0.41) ESR2ESR1RECQLKDM4EMAPK1
SCHEMBL21202802 0.77 ESR2 (0.39) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL28590299 0.75 ESR1 (0.50) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL10056755 0.74 ESR1 (0.49) ESR2ESR1GRIA1CACNG8CACNG2
SCHEMBL21968774 0.74 KDM4E (0.37) ESR2ESR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023140649-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-27 WO disclosed