SCHEMBL25875555

SCHEMBL25875555

C=C(C)C(=O)Oc1ccc(-c2ccc3c(oc4c(C)c(OC(=O)C(=C)C)ccc43)c2F)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.39
MEN1 O00255 2/20 0.39
GAA P10253 2/20 0.39
HTT P42858 2/20 0.39
ADORA3 P0DMS8 1/20 0.37
ELANE P08246 1/20 0.37
GBA1 P04062 1/20 0.37
MAOB P27338 3/20 0.36
MAOA P21397 2/20 0.36
ATM Q13315 1/20 0.35
MAPT P10636 3/20 0.35
HPGD P15428 4/20 0.34
KDM4E B2RXH2 4/20 0.34
LMNA P02545 2/20 0.34
HSD17B10 Q99714 2/20 0.34
GLA P06280 1/20 0.34
MAPK1 P28482 1/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875301 0.91 KMT2A (0.37) KMT2AMEN1GAAHTTADORA3
SCHEMBL25875667 0.91 KMT2A (0.42) KMT2AMEN1GAAHTTADORA3
SCHEMBL25875982 0.87 MAOA (0.38) KMT2AMEN1GAAHTTADORA3
SCHEMBL25875782 0.86 KMT2A (0.38) KMT2AMEN1GAAHTTADORA3
SCHEMBL25876384 0.86 ELANE (0.35) KMT2AMEN1ADORA3ELANEATM
SCHEMBL25875672 0.86 KMT2A (0.43) KMT2AMEN1GAAHTTADORA3
SCHEMBL25873934 0.84 GBA1 (0.43) KMT2AGAAHTTGBA1MAOB
SCHEMBL25875553 0.84 KMT2A (0.39) KMT2AMEN1GAAHTTADORA3
SCHEMBL25875786 0.84 KMT2A (0.37) KMT2AMEN1GAAHTTADORA3
SCHEMBL25874210 0.82 GBA1 (0.49) KMT2AGAAHTTGBA1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed