SCHEMBL25875799

SCHEMBL25875799

CCCCC(C)c1ccc(OC(F)(F)C(F)(F)C(C)(CC)CC)cc1C

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
XBP1 P17861 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TP53 P04637 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31
KDM4E B2RXH2 2/20 0.30
PDE2A O00408 1/20 0.30
CARM1 Q86X55 1/20 0.30
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30
ALOX5 P09917 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875791 0.93 TP53 (0.35) TP53CYP2D6CYP2C9ALOX15CYP2C19
SCHEMBL23766650 0.76 GAA (0.32) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL7881747 0.69 TLR8 (0.35)
SCHEMBL9284758 0.69 TLR8 (0.35)
SCHEMBL16442495 0.68 PDE2A (0.46) L3MBTL1PDE2AALOX5PPARG
SCHEMBL9234391 0.68 PDE2A (0.46) L3MBTL1PDE2AALOX5PPARG
SCHEMBL18704829 0.66 ESR1 (0.42) GAATP53ALOX15KDM4ELMNA
SCHEMBL20909679 0.65 EPHX2 (0.38) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL23766643 0.65 NPC1 (0.47)
SCHEMBL23766634 0.65 NPC1 (0.38) ATML3MBTL1CYP2C9ALOX15CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed