Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25875779 | 0.90 | L3MBTL1 (0.36) | CYP2C9L3MBTL1LMNAKIF11CETP | |
| SCHEMBL21791776 | 0.89 | NPC1 (0.39) | NPC1RAB9ACYP2C9POLBL3MBTL1 | |
| SCHEMBL23766643 | 0.83 | NPC1 (0.47) | NPC1RAB9AMAPTMAOB | |
| SCHEMBL17552755 | 0.82 | KIF11 (0.49) | NPC1RAB9ACYP2C9POLBL3MBTL1 | |
| SCHEMBL12464283 | 0.79 | NPC1 (0.44) | NPC1RAB9ACYP2C9POLBL3MBTL1 | |
| SCHEMBL15356141 | 0.77 | NPC1 (0.43) | NPC1RAB9ACYP2C9POLBL3MBTL1 | |
| SCHEMBL15356135 | 0.77 | NPC1 (0.43) | NPC1RAB9ACYP2C9POLBL3MBTL1 | |
| SCHEMBL3435840 | 0.75 | KIF11 (0.46) | NPC1RAB9ACYP2C9POLBLMNA | |
| SCHEMBL13191971 | 0.74 | TP53 (0.52) | NPC1RAB9ACYP2C9POLBL3MBTL1 | |
| SCHEMBL15356133 | 0.73 | NPC1 (0.40) | NPC1RAB9ACYP2C9POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253786-A1 | FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME | DAIKIN INDUSTRIES, LTD. (JP) | 2021-08-19 | — | — | US | disclosed |