SCHEMBL25876386

SCHEMBL25876386

C=C(C)C(=O)OCCCc1ccc(-c2ccc3c(oc4c(C(F)(F)F)c(OC(=O)C(=C)C)ccc43)c2F)cc1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 7/20 0.36
NR1H2 P55055 6/20 0.36
PPARD Q03181 5/20 0.33
PPARA Q07869 5/20 0.33
PPARG P37231 4/20 0.33
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25876565 0.94 NR1H3 (0.37) NR1H3NR1H2PPARDPPARAPPARG
SCHEMBL25875449 0.93 NR1H2 (0.34) NR1H3NR1H2PPARDPPARAPPARG
SCHEMBL25876477 0.91 NR1H3 (0.36) NR1H3NR1H2PPARDPPARAPPARG
SCHEMBL25875299 0.91 POLB (0.33) NR1H3NR1H2POLBAPEX1HTT
SCHEMBL25876485 0.90 NR1H3 (0.35) NR1H3NR1H2PPARDPPARAPPARG
SCHEMBL25876635 0.89 NR1H3 (0.34) NR1H3NR1H2PPARDPPARAPPARG
SCHEMBL25875559 0.88 MPL (0.34) NR1H3NR1H2PPARDPPARAPOLB
SCHEMBL25876705 0.88 NR1H2 (0.32) NR1H3NR1H2
SCHEMBL25875784 0.88 NR1H2 (0.34) NR1H3NR1H2PPARDPPARAPPARG
SCHEMBL25875986 0.87 MAOA (0.35) POLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed