Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903086 | 0.87 | GBA1 (0.43) | ACHEACACBPOLBSMN1; SMN2LMNA | |
| SCHEMBL25877128 | 0.84 | PIK3CA (0.48) | PIK3CAACHEPIK3CDPIK3R1PIK3CB | |
| SCHEMBL7457917 | 0.83 | PIK3CA (0.59) | PIK3CAACACBPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL31706055 | 0.82 | POLB (0.54) | PIK3CAACHEPIK3CDPIK3R1PIK3CB | |
| SCHEMBL3116636 | 0.82 | POLB (0.54) | PIK3CAACHEPIK3CDPIK3R1PIK3CB | |
| SCHEMBL3112205 | 0.82 | HTT (0.58) | PIK3CAACHEPIK3CDPIK3R1PIK3CB | |
| SCHEMBL20745726 | 0.81 | CRBN (0.53) | PIK3CAACHEPIK3CDPIK3R1PIK3CB | |
| Lithium Ion SCHEMBL31705478 | 0.80 | PIK3CA (0.47) | PIK3CAACHEPIK3CDPIK3R1PIK3CB | |
| SCHEMBL17827961 | 0.76 | PIK3CA (0.51) | PIK3CAACHEPIK3CDPIK3R1PIK3CB | |
| SCHEMBL18765579 | 0.76 | PIK3CA (0.43) | PIK3CAACHEPIK3CDPIK3R1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |