Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 3/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116636 | 0.86 | POLB (0.54) | PIK3CAPIK3R1PIK3CDPIK3CBEIF2AK2 | |
| SCHEMBL3112205 | 0.86 | HTT (0.58) | PIK3CAPIK3R1PIK3CDPIK3CBACACB | |
| SCHEMBL31706055 | 0.86 | POLB (0.54) | PIK3CAPIK3R1PIK3CDPIK3CBEIF2AK2 | |
| SCHEMBL2035264 | 0.86 | POLB (0.51) | PTGS2ACACBNPC1RAB9APOLB | |
| SCHEMBL28071006 | 0.84 | POLB (0.54) | PTGS2ACACBNPC1RAB9APOLB | |
| SCHEMBL20745726 | 0.84 | CRBN (0.53) | PIK3CAPIK3R1PIK3CDPIK3CBACACB | |
| SCHEMBL25877125 | 0.84 | PIK3CA (0.45) | PIK3CAPIK3R1PIK3CDPIK3CBACACB | |
| Lithium Ion SCHEMBL31705478 | 0.84 | PIK3CA (0.47) | PIK3CAPIK3R1PIK3CDPIK3CBACACB | |
| SCHEMBL7457917 | 0.81 | PIK3CA (0.59) | PIK3CAACACBPOLBLMNAHSD17B10 | |
| SCHEMBL29484630 | 0.78 | ALDH1A1 (0.56) | PIK3CAPOLBACHEHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |