Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 3/20 | 0.66 |
| ▸ | YAP1 | P46937 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 5/20 | 0.34 |
| ▸ | TLR1 | Q15399 | 5/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25877124 | 0.84 | TEAD1 (0.71) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL25877140 | 0.83 | TEAD1 (0.67) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL30503081 | 0.83 | TEAD1 (0.67) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL21090737 | 0.82 | TEAD1 (0.66) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL30683314 | 0.81 | TEAD1 (0.65) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL21054618 | 0.81 | TEAD1 (0.65) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL27035571 | 0.81 | TEAD1 (0.65) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL30061318 | 0.81 | TEAD1 (0.65) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL26603003 | 0.81 | TEAD1 (0.65) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL25314394 | 0.81 | TEAD1 (0.67) | TEAD1YAP1TSHRL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136645-A1 | NOVEL AMINOBENZENE DERIVATIVE HAVING CANCER CELL GROWTH INHIBITORY EFFECT, AND PREVENTIVE OR THERAPEUTIC PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | 주식회사 대웅제약 | 2023-07-20 | — | — | WO | disclosed |