Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 3/20 | 0.65 |
| ▸ | YAP1 | P46937 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 5/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 5/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26602926 | 0.90 | TEAD1 (0.64) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL26603108 | 0.89 | TEAD1 (0.63) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL26665090 | 0.86 | TEAD1 (0.59) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL26665094 | 0.85 | TEAD1 (0.47) | TEAD1YAP1EGFRKDRFGFR1 | |
| SCHEMBL25877124 | 0.83 | TEAD1 (0.71) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL25877140 | 0.82 | TEAD1 (0.67) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL30503081 | 0.82 | TEAD1 (0.67) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL21090737 | 0.81 | TEAD1 (0.66) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL25877139 | 0.81 | TEAD1 (0.66) | TEAD1YAP1TSHRL3MBTL1EGFR | |
| SCHEMBL30061318 | 0.80 | TEAD1 (0.65) | TEAD1YAP1TSHRL3MBTL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023204822-A1 | PHENYL PHOSPHINE OXIDE COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023204822-A1 | PHENYL PHOSPHINE OXIDE COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |