Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25877650 | 0.87 | KDM4E (0.55) | KDM4ESMN1; SMN2LMNARAB9APOLB | |
| SCHEMBL25313050 | 0.85 | KDM4E (0.51) | KDM4ESMN1; SMN2LMNARAB9APOLB | |
| SCHEMBL29466348 | 0.85 | KDM4E (0.51) | KDM4ESMN1; SMN2LMNARAB9APOLB | |
| SCHEMBL25310936 | 0.84 | KDM4E (0.58) | KDM4ESMN1; SMN2LMNARAB9APOLB | |
| SCHEMBL25882701 | 0.80 | KDM4E (0.56) | KDM4ESMN1; SMN2LMNARAB9APOLB | |
| SCHEMBL29466341 | 0.80 | GSK3A (0.47) | RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL25878075 | 0.80 | GSK3A (0.47) | RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL25310339 | 0.77 | KDM4E (0.53) | KDM4ESMN1; SMN2LMNARAB9APOLB | |
| SCHEMBL25313124 | 0.77 | GSK3A (0.45) | RAB9AMAPTNPC1MAPK1 | |
| SCHEMBL25311688 | 0.76 | KDM4E (0.54) | KDM4ESMN1; SMN2LMNARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |