Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.82 |
| ▸ | EYA2 | O00167 | 1/20 | 0.82 |
| ▸ | APP | P05067 | 1/20 | 0.82 |
| ▸ | ACE | P12821 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 4/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.78 |
| ▸ | BLM | P54132 | 2/20 | 0.78 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.78 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.78 |
| ▸ | DRD1 | P21728 | 1/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.78 |
| ▸ | DRD3 | P35462 | 1/20 | 0.78 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL28388749 | 0.92 | TDP1 (0.78) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL3810357 | 0.91 | TDP1 (0.88) | TDP1EYA2APPACETSHR | |
| Nitrilotriacetic Acid SCHEMBL28331324 | 0.91 | TDP1 (0.67) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL9128547 | 0.91 | TDP1 (0.88) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL8607480 | 0.91 | TDP1 (1.00) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL8624198 | 0.91 | TDP1 (1.00) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL15136 | 0.91 | TDP1 (1.00) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL1373 | 0.91 | TDP1 (1.00) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL3035039 | 0.91 | TDP1 (1.00) | TDP1EYA2APPACETSHR | |
| Edetic Acid SCHEMBL16714076 | 0.91 | TDP1 (1.00) | TDP1EYA2APPACETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039699-B | Ultra-large-specification thin porcelain plate with negative ion function and production method thereof | 杭州诺贝尔陶瓷有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-111533579-B | Ultra-large thin porcelain plate with negative ion function and manufacturing method thereof | 杭州诺贝尔陶瓷有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-111533579-A | Ultra-large thin porcelain plate with negative ion function and manufacturing method thereof | 杭州诺贝尔陶瓷有限公司 | 2020-08-14 | — | — | CN | claimed |
| CN-111039699-A | Ultra-large-specification thin porcelain plate with negative ion function and production method thereof | 杭州诺贝尔陶瓷有限公司 | 2020-04-21 | — | — | CN | claimed |
| US-20110265834-A1 | Intravascular Line and Port Cleaning Methods, Methods of Administering an Agent Intravascularly, Methods of Obtaining/Testing Blood, and Devices for Performing Such Methods | TENNICAN PATRICK O | 2011-11-03 | — | — | US | claimed |
| CN-117599785-A | Noble metal-based catalyst and preparation method and application thereof | 南方科技大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-114045041-B | Modified asphalt and preparation method thereof | 远大洪雨（唐山）防水材料有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-111533579-B | Ultra-large thin porcelain plate with negative ion function and manufacturing method thereof | 杭州诺贝尔陶瓷有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-111039699-B | Ultra-large-specification thin porcelain plate with negative ion function and production method thereof | 杭州诺贝尔陶瓷有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114045041-A | Modified asphalt and preparation method thereof | 远大洪雨（唐山）防水材料有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-111533579-A | Ultra-large thin porcelain plate with negative ion function and manufacturing method thereof | 杭州诺贝尔陶瓷有限公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-111378777-A | Primer set for identifying crude drug and crude drug identification method using the same | 株式会社津村 | 2020-07-07 | — | — | CN | disclosed |
| WO-2009062898-A1 | NEW SYNTHETIC ARGININE SUBSTITUTED PEPTIDES AND THEIR USE | PHARMASURGICS IN SWEDEN AB (SE) | 2009-05-22 | — | — | WO | disclosed |
| EP-1692279-A4 | PRESERVATIVE-CONTAINING VIRUS FORMULATIONS | MERCK & CO INC (US) | 2006-12-27 | — | — | EP | disclosed |
| EP-1692279-A2 | PRESERVATIVE-CONTAINING VIRUS FORMULATIONS | Merck & Co., Inc. (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005052116-A2 | PRESERVATIVE-CONTAINING VIRUS FORMULATIONS | MERCK & CO., INC. (US) | 2005-06-09 | — | — | WO | disclosed |
| EP-1263461-A1 | ADENOVIRUS FORMULATIONS | Merck & Co., Inc. (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001066137-A1 | ADENOVIRUS FORMULATIONS | MERCK & CO., INC. (US) | 2001-09-13 | — | — | WO | disclosed |
| US-5417887-A | Reduced viscosity, organic liquid slurries of aluminum nitride powder | THE DOW CHEMICAL COMPANY (US) | 1995-05-23 | — | — | US | disclosed |
| US-4493892-A | WATER-ALCOHOL SOLVENT SYSTEM | MEMORIAL HOSPITAL FOR CANCER & ALLIED DISEASES (US) | 1985-01-15 | — | — | US | disclosed |