SCHEMBL25878114

SCHEMBL25878114

CCC(C)CCCC(=O)N1CCCC1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
ATM Q13315 1/20 0.59
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
TDP1 Q9NUW8 1/20 0.58
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 1/20 0.44
NPC1 O15118 2/20 0.42
GNAI3 P08754 1/20 0.40
GNAI1 P63096 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22612678 0.93 L3MBTL1 (0.61) L3MBTL1ATMMEN1KMT2ATDP1
SCHEMBL13667476 0.83 ATM (0.65) L3MBTL1ATMMEN1KMT2ATDP1
SCHEMBL25867597 0.81 ATM (0.63) L3MBTL1ATMMEN1KMT2ATDP1
SCHEMBL12197980 0.81 ATM (0.63) L3MBTL1ATMMEN1KMT2ATDP1
SCHEMBL21016150 0.78 L3MBTL1 (0.63) L3MBTL1ATMMEN1KMT2ATDP1
SCHEMBL16604260 0.78 L3MBTL1 (0.54) L3MBTL1MEN1KMT2ATDP1POLB
SCHEMBL25867751 0.77 ATM (0.57) L3MBTL1ATMMEN1KMT2ATDP1
SCHEMBL14300014 0.77 L3MBTL1 (0.47) L3MBTL1ATMMEN1KMT2ATDP1
SCHEMBL10082173 0.77 L3MBTL1 (0.47) L3MBTL1ATMMEN1KMT2ATDP1
SCHEMBL28873929 0.77 L3MBTL1 (0.53) L3MBTL1ATMMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 WO disclosed