SCHEMBL25878132

SCHEMBL25878132

CC(C)(C)c1nc(-c2ccccc2)nc2ccc3ccccc3c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
LMNA P02545 1/20 0.50
RECQL P46063 1/20 0.50
RAB9A P51151 1/20 0.50
ABCG2 Q9UNQ0 3/20 0.44
TYMS P04818 2/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PDE5A O76074 3/20 0.40
ACP1 P24666 2/20 0.40
TP53 P04637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
TSPO P30536 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10315758 0.80 ABCG2 (0.54) MAPTSMN1; SMN2ABCG2ATMTDP1
SCHEMBL25817326 0.80 TYMS (0.46) MAPTNPC1LMNARAB9ATYMS
SCHEMBL22097081 0.80 TYMS (0.50) MAPTSMN1; SMN2NPC1LMNARAB9A
SCHEMBL19161272 0.78 ABCG2 (0.51) MAPTSMN1; SMN2LMNARECQLRAB9A
SCHEMBL25931444 0.78 MAPT (0.56) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL24623028 0.75 MAPT (0.41) MAPTNPC1LMNARAB9AABCG2
SCHEMBL19161949 0.75 SMN1; SMN2 (0.42) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL19162432 0.74 AURKA (0.42) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL19162434 0.73 MAPT (0.42) MAPTSMN1; SMN2NPC1LMNARECQL
SCHEMBL19161947 0.73 AURKA (0.49) MAPTSMN1; SMN2LMNARECQLRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM MAPT 1215/4885SMN1; SMN2 1669/4885NPC1 1759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.