Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 9/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.49 |
| ▸ | PRKCG | P05129 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | MARK3 | P27448 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.49 |
| ▸ | BLK | P51451 | 2/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25878075 | 0.92 | GSK3A (0.47) | AURKAAURKBNPC1RAB9ACHEK1 | |
| SCHEMBL29466341 | 0.92 | GSK3A (0.47) | AURKAAURKBNPC1RAB9ACHEK1 | |
| SCHEMBL25312057 | 0.91 | AURKA (0.45) | AURKAAURKBNPC1RAB9ACHEK1 | |
| SCHEMBL29466326 | 0.89 | MEN1 (0.49) | AURKAAURKBRAB9AMAPK1MAPT | |
| SCHEMBL25878262 | 0.89 | MEN1 (0.49) | AURKAAURKBRAB9AMAPK1MAPT | |
| SCHEMBL25313124 | 0.89 | GSK3A (0.45) | AURKAAURKBNPC1RAB9ACHEK1 | |
| SCHEMBL25883212 | 0.88 | AURKA (0.44) | AURKAAURKBNPC1RAB9ACHEK1 | |
| SCHEMBL25882455 | 0.86 | HRH4 (0.50) | AURKAAURKBNPC1RAB9ACHEK1 | |
| SCHEMBL27180231 | 0.86 | MEN1 (0.45) | AURKAAURKBRAB9AMAPK1MAPT | |
| SCHEMBL25314515 | 0.85 | AURKA (0.47) | AURKAAURKBNPC1RAB9ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |