Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25879368 | 0.87 | LANCL2 (0.62) | LANCL2SIRT1KDM4ESTK33MEN1 | |
| SCHEMBL30471353 | 0.87 | LANCL2 (0.62) | LANCL2SIRT1KDM4ESTK33MEN1 | |
| SCHEMBL17705597 | 0.78 | LANCL2 (0.62) | LANCL2KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL8213569 | 0.74 | LANCL2 (0.59) | LANCL2KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL18426899 | 0.73 | LANCL2 (0.62) | LANCL2KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL29484573 | 0.73 | LANCL2 (0.67) | LANCL2KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL25876068 | 0.73 | LANCL2 (0.67) | LANCL2KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL29466292 | 0.72 | LANCL2 (0.71) | LANCL2KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL3121939 | 0.72 | LANCL2 (0.63) | LANCL2KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL18426847 | 0.72 | HPSE (0.48) | LANCL2SIRT1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |