Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471353 | 1.00 | LANCL2 (0.62) | LANCL2SIRT1STK33AURKACDK1 | |
| SCHEMBL17705597 | 0.90 | LANCL2 (0.62) | LANCL2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL25878657 | 0.87 | LANCL2 (0.49) | LANCL2SIRT1STK33AURKACDK1 | |
| SCHEMBL18426899 | 0.84 | LANCL2 (0.62) | LANCL2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL29466292 | 0.83 | LANCL2 (0.71) | LANCL2MEN1KMT2ANPSR1KDM4E | |
| SCHEMBL8213569 | 0.82 | LANCL2 (0.59) | LANCL2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL17700974 | 0.82 | LANCL2 (0.69) | LANCL2KMT2ANPSR1KDM4ENPC1 | |
| SCHEMBL29466277 | 0.82 | LANCL2 (0.69) | LANCL2KMT2ANPSR1KDM4ENPC1 | |
| SCHEMBL29484573 | 0.81 | LANCL2 (0.67) | LANCL2AURKACDK1CCNB1CDK2 | |
| SCHEMBL25876068 | 0.81 | LANCL2 (0.67) | LANCL2AURKACDK1CCNB1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |