Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | TSSK3 | Q96PN8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484631 | 1.00 | LANCL2 (0.59) | LANCL2SMN1; SMN2CNR2NPC1RAB9A | |
| SCHEMBL25311481 | 0.83 | LANCL2 (0.58) | LANCL2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL25310104 | 0.82 | LANCL2 (0.55) | LANCL2SMN1; SMN2FOXO1CHEK1 | |
| SCHEMBL25878837 | 0.81 | LANCL2 (0.74) | LANCL2SMN1; SMN2NPC1RAB9ACHEK1 | |
| SCHEMBL8213569 | 0.80 | LANCL2 (0.59) | LANCL2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL25312272 | 0.79 | LANCL2 (0.69) | LANCL2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL30471353 | 0.79 | LANCL2 (0.62) | LANCL2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL17705597 | 0.79 | LANCL2 (0.62) | LANCL2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL18426899 | 0.79 | LANCL2 (0.62) | LANCL2SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL25879368 | 0.79 | LANCL2 (0.62) | LANCL2SMN1; SMN2NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |